Integrative Design / Extremes approaches design through the lens of extremes and from the perspective of outer space. This involves a continuous act of zooming out to understand systems as a whole and zooming in to engage with all scales—down to the microbial—on the essentials of life and architecture. This systems-based mindset forms the foundation of Integrative Design / Extremes The group proposes three core strategies: (1) Adaptability as a basis for sustainability (2) Replicating extra/terrestrial systems, (3) A new vernacular—low-energy, digitally fabricated, and biologically active materials.